Explores the kinetics for biochemical reactions and structural changes. Micro- and nano-encapsulation of process- and digestion-sensitive molecules. Raw, minimally processed, optimally processed, and overprocessed foods. Chemical characterization of functional biomolecules, ingredients and foods.
Early Bird Registration Deadline: Friday May 23, 2025
Dive into Çeşme’s clear waters to experience vibrant marine life.
Friday April 25, 2025
Early Bird Registration Deadline:
Friday May 23, 2025
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MaCKiE 2025
The International Conference on Mathematics in (bio/food) Chemical Kinetics and Engineering (MaCKiE) 2025 will be held in Izmir, Türkiye from September 3 -5 in the beautiful seaside hotel & spa of Altın Yunus, Çeşme (Izmir). It is the eleventh event of the series, with previous meetings in Ghent, Belgium (2002, 2009, 2015, 2018), Houston, USA (2007), Heidelberg, Germany (2011), Chennai, India (2013), Budapest, Hungary (2017), Shanghai, China (2021) and Berlin, Germany (2023). Since its first event in 2002, the MaCKiE conference has been organized once every two years.
The meeting aims to bring together scientists and engineers interested in the application of mathematical modeling to describe physicochemical phenomena in chemical and biological processes.
MACKiE 2025 SPECIAL : FOOD MaCKiE
FOOD MaCKiE 2025 is a new initiative with a program of parallel sessions launched this year to cover physics-based modelling approaches for conventional and innovative food processing. Kinetics studies to describe microbial and chemical changes are also included. Considering the sustainability requirements in food manufacturing, technologies for the use of byproducts, waste and new sources of foods and food ingredients will be highlighted too. Speakers will engage attendees in conversations to translate scientific efforts into science and engineering advances ensuring food safety. Food security and sustainability will also be covered since food production is facing limits in the availability of land, water and other critical resources. Oral and poster presentation will be enriched by a Short Course addressing advances in product, process and packaging design. Finally, FOOD MaCKiE invites all attendees to the Round Table on “Digitalization and Modeling of the Food Processing Plant” to identify collaboration opportunities.
Conference Invitation
Researchers from all over the world are invited to attend the Mathematics in (bio/food) Chemical Kinetics and Engineering (MaCKiE) workshop between 3 and 5 September, 2025 in the vibrant city of Izmir (Smyrna), a historic jewel on the Aegean coast of Anatolia close to Troy, where ancient Greco-Roman heritage meets modern-day dynamism. With its rich cultural tapestry, sun-kissed beaches, and welcoming atmosphere, Izmir promises to be an inspiring backdrop for the exchange of groundbreaking ideas.
The acronym MaCKiE, originally coined by Guy B. Marin, Grigoriy Yablonsky and Denis Constales of Ghent University Belgium, comes from the title of the conference and is phonetically indistinguishable from “makkie” in Dutch, optimistically meaning a ‘walk in the park’ (something that is easy to do or easy to complete). Interestingly, it also bears a phonetic similarity to the Turkish word “maki,” which refers to a type of vegetation that blankets the soil after a forest fire. Maki plays a crucial role in creating a temporary canopy that allows new life to emerge thus representing the nurturing of new ideas and thoughts that need to be protected before they can truly thrive.
We look forward to welcoming you to Izmir in September !
Conference Themes
- General MaCKiE
- Food MaCKiE
Expanding the Fundamentals
Applied Kinetic Modeling and Microkinetic Models
Explores the role of applied kinetic modeling and microkinetic models in optimizing chemical processes. Focuses on the insights that drive advancements in catalysis, reaction engineering, and process optimization.
Ab initio-based Kinetics or Stochastic Processes
Explores the role of stochastic processes in understanding chemical and biological kinetics at the molecular level. Focuses on the advanced stochastic simulation techniques to capture the intricacies of reaction dynamics in gas or liquid phase, including catalytic and cellular environments.
Resolving Complexity and Challenges
Multi-scale Modeling in Kinetics and Transport
Explores the integration of multi-scale modeling techniques to understand the relation between kinetics and fluid dynamics in complex chemical and biological systems. Focuses on the coupling between models that describe microscopic, mesoscopic or macroscopic behavior.
AI based (bio/food)Chemical Engineering Models and Applications
Explores the transformative impact of artificial intelligence (AI) in dynamic processes by integrating innovative data-driven techniques, such as machine learning. Focuses on the application of Al based methods to analyze kinetic data, predict process outputs, and develop real-time control strategies for chemical and biological processes.
Food Healthfulness and Delivering Consumer-Group Targeted Nutrition
Explores conventional and omics characterization of functional biomolecules for healthy growth, aging, and food technology applications. Examines human interactions with food through simulations and the bioavailability of functional molecules.
Application to New Processes
(Bio/Food)Chemical Reaction Mechanisms and Process Design
Explores understanding of how molecular interactions and kinetics can optimize the design and efficiency of processes in chemical and biological processes. Focuses on advancements in reactor design, enhancing productivity, and addressing challenges in industrial applications, such as food processing and waste management.
Modeling Sustainable Processes: Electrification and Decarbonization
Explores new chemical processes with use of modeling and applied mathematics. Welcomes the use of novel reaction engineering and processing methods, such as electrochemistry, plasmas, high pressure, microwave, ultrasound, etc., and focuses on how innovative models can simulate, optimize and improve sustainable processes, with the aim of increasing energy efficiency and reducing CO2 emissions.
Emerging Processing for Development of a Sustainable and Environmentally Friendly Food System
Explores green technologies for development of valorization processes for byproducts and waste. Packaging and processing compliance with circular economy principles. Innovations and commercial challenges for sustainable food manufacturing. Innovations and challenges of 3D and 4D food printing.
Mathematical Modeling for Food Processing Design and Optimization
Explores mathematical modeling for food manufacturing in Industry x.0. Digital twin applications with AI and ML. Mathematical modeling and applications of conventional and novel processing technologies. Microbial and enzyme inactivation by novel technologies.
MACKIE WORKSHOPS
Probabilistic Food Product, Processing and Packaging Engineering Design
Covers practical tools to manage model and data variability and uncertainty to obtain designs meeting targets with a specified confidence level. Knowledge to be acquired by hands-on shelf-life, safety and cost determinations based on published data and to optimize design parameters, ensuring robust decision-making in real-world scenario. Attendees must have laptops and good Excel skills which will be the platform used in this course.
The instructor and the two assistants will use a PC to assist attendees. Registration compulsory.
Lecturer: Prof. Dr. J. Antonio Torres (Tecnológico de Monterrey, Mexico) 03.09.2025, full day in-person.
(Outline TBA)
(Bio/Food) Chemical Engineering Simulations: OpenFOAM Techniques for Fluid Flow and Heat Transfer
Provides hands-on experience with OpenFOAM, one of the leading open-source CFD tools, to simulate fluid flow and heat transfer processes in engineering. Knowledge and insights to be acquired is how to model and optimize real-world (bio/food) chemical engineering industrial problems and enhance understanding of transport phenomena. Attendees must have laptops and basic programming skills which will be the platform used in this course.
Step-by step description of installing OpenFOAM in laptops will be provided in advance. Registration compulsory.
Lecturers: Nikhil Bhamare and Meltem Turan (Simuligence, Lithuania), 01.09.2025, full day on-line.
(Outline TBA)
OUR Special Issue Journals
Founding Members of MaCKiE
Professor Emeritus Guy B. Marin
Guy B. Marin is a founding member of the Laboratory for Chemical Technology (LCT) and the Center of Sustainable Chemistry (CSC) at Ghent University. Prior to that, after a stay as Fulbright fellow at Stanford University and its spin-off Catalytica Associates, he has been teaching at the Department of Chemical Engineering and Chemistry of Eindhoven University of Technology. His research on chemical kinetics and reactor engineering, focusing on modeling and designing chemical processes, led to the spinoff company AVGI BV. That year, he was elected to the Royal Flemish Academy of Belgium for Sciences and Arts. He co-authored two books and over 700 high-impact papers and is co-editor-in-chief of “Current Opinion in Chemical Engineering.” His ERC Advanced grant fostered transdisciplinary work on process intensification and circular economy transition.
Professor Grigoriy S. Yablonsky
Grigoriy S. Yablonsky is a Professor at Washington University in St. Louis, USA. He is a renowned expert in chemical kinetics and engineering, with a focus on heterogeneous catalysis. His theory of critical kinetic behavior, co-developed with Valeriy Bykov, is widely applied by global research teams. Yablonsky collaborated with Alexander Gorban on chemical thermodynamics and irreversible reaction theory. He co-authored Kinetics of Chemical Reactions: Decoding Complexity with Guy Marin and Denis Constales and partnered with John Gleaves to enhance catalyst characterization through the TAP technique. Yablonsky, Marin and Constales introduced the innovative ‘joint kinetics’ approach, analyzing experimental "batteries" to reveal chemical mechanisms. An Honorary Professor at Ghent University, he received the James B. Eads Award (2013) and the MaCKiE Lifetime Achievement Award.
Dr. Denis Constales
Denis Constales is an Associate Professor in the Faculty of Engineering and Architecture at Ghent University, specializing in applied mathematical analysis. His research spans classical and numerical analysis, chemical engineering, kinetics, surveying, and hypercomplex analysis. He has made significant contributions to modeling chemical processes, focusing on reaction kinetics and catalyst deactivation. His work applies integral transforms and special functions to solve complex engineering problems. With over 100 publications, Denis Constales is a prolific researcher and a dedicated educator, mentoring students in mathematical analysis and its engineering applications. His interdisciplinary approach bridges theoretical mathematics and practical engineering, addressing real-world challenges through innovative mathematical solutions.
A Special Session honoring the contributions of Professor Grigoriy S. Yablonsky on the occasion of his 85th birthday is being planned.
Organizing Members of Mackie 2025
Kevin Van Geem
Conference Co-Organizer
Ghent University, Belgium
Abhishek Dutta
Conference Principal Organizer
Izmir Institute of Technology, Türkiye
Necip B. Üner
Conference Co-Organizer
Middle East Technical University, Türkiye
Abhishek Dutta
Conference Principal Organizer
Izmir Institute of Technology, Türkiye
Necip B. Üner
Conference Co-Organizer
Middle East Technical University, Türkiye
Kevin Van Geem
Conference Co-Organizer
Ghent University, Belgium
Organizing members of Food MaCKiE 2025
Esra Çapanoğlu Güven
Istanbul Technical University, Türkiye
Semanur Yıldız Özdemir
Sakarya University, Türkiye
Important Dates
3-5 September, 2025
MaCKiE Conference
Sunday 2nd March, 2025
Abstract Submission Deadline
Sunday 6th April, 2025
Author Notification Deadline
Friday 11th April, 2025
Early Registration Deadline
Tuesday 6th May, 2025
Late Registration Deadline
To be announced later
Full Papers for Conference Special Issue
| MaCKiE Conference : 3-5 September, 2025 |
| Abstract Submission Deadline : Sunday 2nd March, 2025 |
| Author Notification Deadline : Sunday 6th April, 2025 |
| Early Registration Deadline : Friday 11th April, 2025 |
| Late Registration Deadline : Tuesday 6th May,2025 |
| Full Papers for Conference Special Issue : To be announced later |
